Antidepressants and Falls: Risks, Causes, and What to Do

When you take antidepressants, medications used to treat depression by balancing brain chemicals like serotonin. Also known as SSRIs or SNRIs, they help millions feel better—but for older adults, they can make falls more likely. That’s not a side effect you hear about often, but it’s real. Studies show seniors on these drugs are up to 40% more likely to fall, and falls are the leading cause of injury and death in people over 65.

Why does this happen? SSRIs, a common class of antidepressants including sertraline and escitalopram lower serotonin not just in the brain but also in platelets, which affects balance and coordination. They can also cause dizziness, low blood pressure when standing, and slower reaction times. Combine that with age-related muscle loss, poor vision, or other meds—and the risk climbs fast. Even more concerning: Beers Criteria, a trusted list of potentially harmful drugs for older adults flags several antidepressants as high-risk for seniors, especially those with a history of falls or bone thinning.

It’s not all bad news. Not every antidepressant carries the same risk. Some, like bupropion, are less likely to cause dizziness or low blood pressure. And sometimes, switching to a different drug or lowering the dose can make a big difference. But you can’t guess your way through this. If you or a loved one is on antidepressants and has started stumbling, tripping, or feeling lightheaded, it’s time to talk to a doctor. Don’t stop the med—just get it reviewed. Many seniors take five or more drugs at once, and that’s where things get dangerous. Antidepressants and falls are a quiet crisis in aging populations, but one that’s fixable with the right awareness.

Below, you’ll find real posts from people who’ve dealt with this—whether it’s spotting dangerous drug combos, understanding how SSRIs affect balance, or finding safer alternatives for older adults. These aren’t theory pieces. They’re practical, tested insights from patients, caregivers, and clinicians who’ve seen what works—and what doesn’t.