Naproxen: Uses, Risks, and What You Need to Know Before Taking It

When you reach for a pain reliever, naproxen, a nonsteroidal anti-inflammatory drug used to reduce pain, swelling, and fever. Also known as Aleve, it's one of the most widely used NSAID medications in the U.S. Unlike acetaminophen, naproxen doesn’t just mask pain—it tackles the inflammation causing it. That’s why it’s prescribed for arthritis, tendonitis, menstrual cramps, and even gout flare-ups. But here’s the catch: if you’re taking it daily, you’re playing with fire.

Every time you swallow a naproxen tablet, your body is suppressing enzymes that cause pain—but also ones that protect your stomach lining and keep your kidneys functioning right. That’s why long-term use links to ulcers, high blood pressure, and even heart attacks. Studies show people taking NSAIDs like naproxen for more than a month raise their risk of cardiovascular events by up to 20%. And if you’re on blood thinners or have kidney disease? You’re adding fuel to the fire. It’s not just about dosage—it’s about how long you take it, and what else you’re mixing it with.

It’s not all bad news. For short-term use—say, a bad back or a sprained ankle—naproxen works fast and well. It lasts longer than ibuprofen, so you don’t have to pop pills every four hours. But if you’re using it for chronic pain, you need a plan. Talk to your doctor about alternatives like physical therapy, topical creams, or even low-dose antidepressants for nerve pain. And if you’re buying it over the counter, don’t assume it’s harmless. Many people don’t realize they’re doubling up: naproxen hides in combo cold meds, muscle rubs, and even some sleep aids.

There’s a reason why so many posts here cover drug interactions, bleeding risks, and storage safety. Naproxen doesn’t exist in a vacuum. It’s part of a bigger web—linked to anticoagulants, SSRIs, and even probiotics, since gut health affects how your body handles inflammation. You’ll find posts here that explain how NSAIDs like naproxen can interfere with blood pressure meds, worsen kidney function, and increase bleeding risk when paired with aspirin or warfarin. You’ll also see how people manage side effects like stomach upset, dizziness, and fluid retention. This isn’t just about taking a pill. It’s about understanding what’s happening inside your body when you do.

Whether you’re using naproxen for a weekend of hiking or managing arthritis for years, the goal is the same: relief without damage. The posts below give you real, practical advice—how to spot warning signs, how to reduce side effects, and when to switch to something safer. No fluff. No marketing. Just what you need to know before the next dose.